He discussed what an infection of the heart valve called infective endocarditis is and how it. Treatment guidelines from both the american heart association, endorsed by the. The valves of the heart do not receive any dedicated blood supply. Definition and epidemiology of infective endocarditis. Pathoma video lectures full offline mp4 free download. Anatomy videos for dr ali haseebsurgery free download. Bacterial endocarditis is a bacterial infection of the inner layer of the heart or the heart valves. Endocarditis, infective nord national organization for. Watch our free medical lectures on basic medical sciences and clinical medicine by dr.
Most pathogens identified were viridans streptococci and zoonotic bacteria species, as found in other resourcelimited countries where underlying rheumatic heart disease is common. Najeeb lectures and enjoy it on your iphone, ipad, and. It occurs in the valves and inner lining of your heart called the endocardium. The predisposing factors such as dental plaquesprocedures and compromised valvular heart. Definition clinical classification difference between acute and subacute infective endocarditis etiology causative microorganisms predisposing risk factors pathogenesis of. Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. Im grappling with my online studies in infectious disease at london. The relationship of the immunologic consequences of this antigenemia to the clinical and pathologic findings in endocarditis have been the. Infective endocarditis is a fatal disease if left untreated.
Despite rigorous diagnostic testing, the cause of infective endocarditis was identified for just 60 45. Infective endocarditis guidelines on prevention, diagnosis and treatment of. Infective endocarditis arises when an adherent plateletfibrin nidus becomes secondarily infected and produces vegetations, which in turn may directly damage the endocardial tissue andor valves. It is most commonly caused by bacterial and fungal infections, although noninfective causes of endocarditis occur, this chapter will concentrate on infective causes. Immunology of infective endocarditis sciencedirect. List of drugsmedicine used for infective endocarditis. Endocarditis is inflammation of your hearts inner lining, called the endocardium. Endocarditis can have profound and devastating neurologic consequences. Symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cells.
Infective endocarditis is rare, with a yearly incidence of about 310 per 100 000 people. Infective endocarditis continues to be a challenge for the cardiac physicians. Mri is the imaging modality of choice when investigating the cerebral complications of ie, with studies consistently reporting cerebral infarcts in up to 80% of patients. The epidemiology of infective endocarditis has become more complex with todays myriad healthcareassociated factors that predispose to infection. When a person has bacterial endocarditis, these valves may not be able to work properly. Infective endocarditis is most common among men in their 50s and especially prevalent among africanamericans. To investigate the cumulative incidence of and factors associated with mortality among patients with infective endocarditis ie at thailands largest national tertiary referral center. Infective endocarditis is a bacterial infection of the inner lining of the heart muscle endocardium. Infective endocarditis has been a constant menace in human history with its debilitating consequences. Najeeb has been teaching medical sciences for over 32 years and has helped millions of students master medical sciences with crystal clear concepts. Watch the complete lecture in the members area at endocarditis is inflammation of your hearts inner. Infective endocarditis is a potentially lethal disease that has undergone major changes in both host and pathogen. Dr bhatia discussing on pericardial disease in last minute revision point discussion series duration.
There search for dr najeeb and tadathe channel appears. Intracardiac abscess resulting in complete heart block is an infrequent complication of infective endocarditis. This signs and symptoms information for infective endocarditis has been gathered from various sources, may not be fully accurate, and may not be the full list of infective endocarditis signs or infective endocarditis symptoms. Najeeb lectures are the worlds most popular medical lectures. The continuing evolution of antimicrobial resistance among common pathogens that cause infective endocarditis. We use your linkedin profile and activity data to personalize ads and to show you more relevant ads. Furthermore, signs and symptoms of infective endocarditis may vary on an individual basis for each patient. Infective endocarditis congenital heart disease cove. Bacterial infection is most common for ie, but other pathogens such as fungi, richettsia, chlamydia and virus, can also cause ie. Definitions a microbial infection of a cardiac valve or the endocardium caused by bacteria, fungi, or chlamydia often categorized as acute or subacute based on the rapidity of the clinical course alternatively described by type of risk factor e. This inner lining also covers the heart valves, and it is these valves which are primarily affected by infective endocarditis. Dr watt is a tropical medicine consultant at the international emerging infectious diseases program in the thailand ministry of public healthus centers for disease control and prevention collaboration. Master medical sciences with crystal clear concepts.
Infective endocarditis ie is an infection involving the endocardial surface of the heart, including the valvular structures, the chordae tendineae, sites of septal defects, or the mural endocardium. Infective endocarditis presenting as complete heart block. Infective endocarditis ie is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. Najeeb lectures worlds most popular medical lectures. Gregg silverman joined first edition monday for dr. His sense of humor and brilliant illustrations make everything stick well in your memory. Cerebrovascular complications in patients with leftsided infective endocarditis are common. Nearly two thirds of cases occur in conjunction with preexisting heart conditions, surgeries, or defects. Citations may include links to fulltext content from pubmed central and publisher web sites. Infective endocarditis symptoms, diagnosis and treatment. A look at the new infective endocarditis guidelines. Infective endocarditis dr mohammad ali khalid, assistant professor of medicine, rmc and allied teaching hospitals. Infective endocarditis presenting as complete heart block with an unexpected finding of a cardiac abscess and purulent pericarditis. Moreillon discuss the epidemiology, pathogenesis, prophylaxis, diagnosis, and management of infective endocarditis.
Bhatia medical coaching institute, dbmci 9,856 views. Najeeb uses handdrawn illustrations to empower your learning process because he believes lasting knowledge results from clear concepts. This can force the heart to work harder to get blood out to the body. Im grappling with my online studies in infectious disease at london school of hygiene and tropical medicine. Background despite advances in medical, surgical, and critical care interventions, infective endocarditis remains a disease that is associated with considerable morbidity and mortality. Most presentations of endocarditis are limited to valvular and perivalvular structures, with. Symptoms may include fever, small areas of bleeding into the skin, heart murmur, feeling tired, and low red blood cell count. Be is not common, but can happen if bacteria from another part of your body enter your bloodstream. Infective endocarditis investigations bmj best practice. It occurs due to bacterial and fungal infection and as serious complication of congenital heart disease and reheumatic valvular heart disease.
Infective endocarditis ie mmostost cases ooff ie n ie notot ppreventablereventable wiwithth pprophylaxisrophylaxis absent history of a lesion no controlled studies of efficacy. Microsoft powerpoint 09 lecture 9 infective endocarditis compatibility mode. While we have innovated too much more than what is required. Unlimited access to the largest elibrary of professional videos, images, documents, courses. Definition infective endocarditis is the inflammation of the endocardium, the inner lining of the heart. Native valve ie prosthetic valve ie intravenous drug abuse ivda ie nosocomial ie 3. Complications may include valvular insufficiency, heart failure, stroke, and kidney failure the cause is typically a bacterial infection and less commonly a fungal infection. Noninfective rheumatic endocarditis atypical verrucous endocarditis non bacterial thrombotic endocarditis b. Bacterial, or infective, endocarditis be is a type of infection. Infective endocarditis ie is an endovascular infection and inflammation with vegetation formation, usually caused by infectious agents. Antibiotics form the mainstay of treatment of infective endocarditis.
Najeeb is the single most spectacular medical teacher you will ever have. If the infection remains untreated, multiplying bacteria may eventually destroy the valves and result in heart failure. Clarke persistent bacteremia is characteristic of infectioe endocarditis. To begin with, an empirical antibiotic treatment is. Pubmed comprises more than 26 million citations for biomedical literature from medline, life science journals, and online books. Infective bacterial endocarditis other infective types tuberculosis, syphilitic, fungal, viral, rickettsial infective endocarditis febrile. Infective endocarditis ie is an infectious and inflammatory process of endothelial lining of the heart structures and valves. Infective endocarditis is an infection of the inner surface of the heart, usually the valves. Infective endocarditis esc guidelines on prevention, diagnosis. List of drugs used to treat the medical condition called infective endocarditis. The condition associated with the highest risk of developing infective endocarditis ie is. Moreover, changes in pathogen prevalence, in particular a more common. He is principal investigator of a project that seeks to define the causes and risk factors of infective endocarditis in thailand.
Definition infective endocarditis ie, a microbial infection of the heart valves or other endocardial tissue, usually is associated with an underlying cardiac defect, primarily by bacteria. Patients with congenital heart defects are especially prone to endocarditis. Infective endocarditis in northeastern thailand volume. In most cases, the neurologic sequelae are present before the initiation of antimicrobial therapy 76%. Our videos are trusted by 80% of medical students in 190 countries. Click on the drug to find more information including the brand names,dose,sideeffects, adverse events, when to. He teaches all the basic medical sciences like gross anatomy. Pdf infective endocarditis in northeastern thailand. These valves help the blood flow through the heart and out to the body.